High Doses Of ADHD Drugs Can Lead To Long-Term Changes In The Brain, Study Says

A new study has founded that adolescents who are frequently exposed to high doses of amphetamine, a stimulant that is used to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, are at-risk of developing long-term changes in their brain function...

"The dopamine system, which continues to develop throughout adolescence and young adulthood, is a primary target of psychostimulant drugs like amphetamine," said Joshua Gulley, a psychology professor at the University of Illinois and the lead investigator of the study. "Changes in dopamine function in response to repeated drug exposure are likely to contribute to the behavioral consequences - addiction and relapse, for example - that abusers experience."

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